Why HPLC Pump?
HPLC Pump generates enormous amount of pressure which helps in efficient separation of API from drug formulation. High pressure helps in getting high resolution and sharp bands on the chromatogram.
Reciprocating Pump
- Suction Stroke -: Reciprocating pump starts with suction stroke. During this phase, the piston or plunger slides away from the cylinder head, forming a low-pressure zone within the cylinder. The suction valve, which is usually a one-way valve, opens, allowing fluid to enter the cylinder from the fluid source or reservoir. The fluid fills the cylinder when the piston or plunger approaches the cylinder head.
- Compression Stroke -: After the suction stroke is completed, the piston or plunger reverses direction and advances towards the cylinder head. This is known as a compression stroke. As the piston or plunger moves, the suction valve closes to prevent fluid backflow. The fluid confined inside the cylinder is compressed, resulting in increased pressure.
- Discharge Stroke -: When the pressure inside the cylinder exceeds the pressure in the discharge line or system, the discharge valve, an additional one-way valve, opens. This commences the discharge stroke. The piston or plunger continues to travel toward the cylinder head, pushing the pressured fluid through the discharge valve and into the discharge line or system.
Syringe Drive Pump
A syringe pump has a simple working principle of converting the rotational motion of a stepper motor to the linear motion of a traveling nut coupled with the threaded screw of the motor, and it delivers precise amounts of fluid by pushing the plunger of a syringe with a pusher block connected to the nut.
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